import matplotlib.pyplot as plt
import matplotlib.gridspec as gridspec
import numpy as np

x = np.linspace(0, 10, 100)
y = np.sin(x)
fig = plt.figure()
gs = gridspec.GridSpec(3, 3)
ax1 = fig.add_subplot(gs[0, :])
ax2 = fig.add_subplot(gs[1, :-1])
ax3 = fig.add_subplot(gs[1:, -1])
ax4 = fig.add_subplot(gs[-1, 0])
ax5 = fig.add_subplot(gs[-1, -2])
ax1.plot(x, y)
ax1.set_title(''''Plot 1'''')
ax2.plot(x, -y)
ax2.set_title(''''Plot 2'''')
ax3.plot(x, y**2)
ax3.set_title(''''Plot 3'''')
ax4.plot(x, -y**2)
ax4.set_title(''''Plot 4'''')
ax5.plot(x, y**3)
ax5.set_title(''''Plot 5'''')
plt.tight_layout()
plt.show()

def plot(tiles,  title=None,ax=None, fs=10, rows=5, cols=5):
        if ax is None:
            fig, ax = plt.subplots(1,figsize=(5,5))  
        border = plt.Rectangle((0, 0), cols, rows, ec=''''k'''', fc=''''w'''', lw=3)
        ax.add_patch(border)
        count=0
        for row in range(0,cols):
            for col in range(rows-1, -1,-1):
                tile = tiles[count]
                if tile == 0: 
                     tile =''''-''''
                cell = plt.Rectangle((row, col), 1, 1, fc=''''orange'''', ec=''''k'''', lw=2, alpha=0.6)
                ax.add_patch(cell)
                ax.text(row + 0.5, col + 0.5, f"{tile}", color=''''black'''', fontsize=fs, va=''''center'''', ha=''''center'''')
                count=count+1
        ax.axis(''''square'''')
        ax.axis(''''off'''')
        if title:
            ax.set_title(title, fontsize=fs)
            
tiles = [ 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60, 61,62, 63, 64, 65, 66 ]
plot(tiles,''''title 1'''', rows=4, cols=4)
plot(tiles,''''title 2'''', rows=3, cols=3)

tiles = [ 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60, 61,62, 63, 64, 65, 66 ]

fig = plt.figure()
ax1 = fig.add_subplot(2,2, 1)
ax2 = fig.add_subplot(2,2, 2)
ax3 = fig.add_subplot(2,2, 3)
ax4 = fig.add_subplot(2,2, 4)

plot(tiles,''''5x5 1'''',ax=ax1, rows=5, cols=5)
plot(tiles,''''4x4 2'''',ax=ax2, rows=4, cols=4)
plot(tiles,''''3x3 3'''',ax=ax3, rows=3, cols=3)
plot(tiles,''''2x2 4'''',ax=ax4, rows=2, cols=2)